Review



pc1 hyper c199s  (Addgene inc)


Bioz Verified Symbol Addgene inc is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Addgene inc pc1 hyper c199s
    Pc1 Hyper C199s, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pmc12719785-83-0-6?v=Addgene+inc
    Average 90 stars, based on 7 article reviews
    pc1 hyper c199s - by Bioz Stars, 2026-08
    90/100 stars

    Images



    Similar Products

    pc1 hyper c199s  (Addgene inc)
    90
    Addgene inc pc1 hyper c199s
    Pc1 Hyper C199s, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pmc12719785-83-0-6?v=Addgene+inc
    Average 90 stars, based on 1 article reviews
    pc1 hyper c199s - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    pc1 hyper 3  (Addgene inc)
    93
    Addgene inc pc1 hyper 3
    Pc1 Hyper 3, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pmc12719785-82-0-6?v=Addgene+inc
    Average 93 stars, based on 1 article reviews
    pc1 hyper 3 - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier
    vsevolod belousov  (Addgene inc)
    93
    Addgene inc vsevolod belousov
    Vsevolod Belousov, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pm41243119-87-22-24?v=Addgene+inc
    Average 93 stars, based on 1 article reviews
    vsevolod belousov - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier
    ermakova et  (Addgene inc)
    93
    Addgene inc ermakova et
    Ermakova Et, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/bio_rxiv__2025__10__07__680983-143-39-43?v=Addgene+inc
    Average 93 stars, based on 1 article reviews
    ermakova et - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier
    hyperred  (Addgene inc)
    93
    Addgene inc hyperred
    Appearance and behavior of the HeLa TPI E105D-GF-HR cell line. Upper panel. Representative images of cells expressing mutant TPI-GFP (green) and a <t>HyPerRed</t> ROS biosensor (orange). Nuclei were counterstained with Hoechst 33342 (blue). Images were acquired on an OPERA Phenix Plus using a 63x water immersion objective in the DAPI, GFP, and Cy3 channel. Lower panel. Quantification of cellular response to test agents reveals desirable (elevated GFP in the absence of nuclear shrinkage and elevated ROS; luminespib) and undesirable activity profiles (elevated GFP correlating with nuclear shrinkage and elevated ROS; CID 3724239). Y-axes show percent increases compared with vehicle-treated cells. Data points are the average of at least three independent biological repeats ± SD. Curves were fitted to a four parameter logistic regression. Green, GFP-TPI levels, red, ROS, blue, nucleus size. Images were subjected to identical linear bitmap stretch for visibility.
    Hyperred, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pmc12707346-50-14-16?v=Addgene+inc
    Average 93 stars, based on 1 article reviews
    hyperred - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier
    vector pc1 cmvp mscarlet  (Addgene inc)
    95
    Addgene inc vector pc1 cmvp mscarlet
    Appearance and behavior of the HeLa TPI E105D-GF-HR cell line. Upper panel. Representative images of cells expressing mutant TPI-GFP (green) and a <t>HyPerRed</t> ROS biosensor (orange). Nuclei were counterstained with Hoechst 33342 (blue). Images were acquired on an OPERA Phenix Plus using a 63x water immersion objective in the DAPI, GFP, and Cy3 channel. Lower panel. Quantification of cellular response to test agents reveals desirable (elevated GFP in the absence of nuclear shrinkage and elevated ROS; luminespib) and undesirable activity profiles (elevated GFP correlating with nuclear shrinkage and elevated ROS; CID 3724239). Y-axes show percent increases compared with vehicle-treated cells. Data points are the average of at least three independent biological repeats ± SD. Curves were fitted to a four parameter logistic regression. Green, GFP-TPI levels, red, ROS, blue, nucleus size. Images were subjected to identical linear bitmap stretch for visibility.
    Vector Pc1 Cmvp Mscarlet, supplied by Addgene inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pmc12135376-392-17-19?v=Addgene+inc
    Average 95 stars, based on 1 article reviews
    vector pc1 cmvp mscarlet - by Bioz Stars, 2026-08
    95/100 stars
    		  Buy from Supplier
    pc1  (Addgene inc)
    93
    Addgene inc pc1
    Appearance and behavior of the HeLa TPI E105D-GF-HR cell line. Upper panel. Representative images of cells expressing mutant TPI-GFP (green) and a <t>HyPerRed</t> ROS biosensor (orange). Nuclei were counterstained with Hoechst 33342 (blue). Images were acquired on an OPERA Phenix Plus using a 63x water immersion objective in the DAPI, GFP, and Cy3 channel. Lower panel. Quantification of cellular response to test agents reveals desirable (elevated GFP in the absence of nuclear shrinkage and elevated ROS; luminespib) and undesirable activity profiles (elevated GFP correlating with nuclear shrinkage and elevated ROS; CID 3724239). Y-axes show percent increases compared with vehicle-treated cells. Data points are the average of at least three independent biological repeats ± SD. Curves were fitted to a four parameter logistic regression. Green, GFP-TPI levels, red, ROS, blue, nucleus size. Images were subjected to identical linear bitmap stretch for visibility.
    Pc1, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pm40295764-258-12-13?v=Addgene+inc
    Average 93 stars, based on 1 article reviews
    pc1 - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier
    pc1 plasmid backbone  (Addgene inc)
    93
    Addgene inc pc1 plasmid backbone
    Appearance and behavior of the HeLa TPI E105D-GF-HR cell line. Upper panel. Representative images of cells expressing mutant TPI-GFP (green) and a <t>HyPerRed</t> ROS biosensor (orange). Nuclei were counterstained with Hoechst 33342 (blue). Images were acquired on an OPERA Phenix Plus using a 63x water immersion objective in the DAPI, GFP, and Cy3 channel. Lower panel. Quantification of cellular response to test agents reveals desirable (elevated GFP in the absence of nuclear shrinkage and elevated ROS; luminespib) and undesirable activity profiles (elevated GFP correlating with nuclear shrinkage and elevated ROS; CID 3724239). Y-axes show percent increases compared with vehicle-treated cells. Data points are the average of at least three independent biological repeats ± SD. Curves were fitted to a four parameter logistic regression. Green, GFP-TPI levels, red, ROS, blue, nucleus size. Images were subjected to identical linear bitmap stretch for visibility.
    Pc1 Plasmid Backbone, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plasmid+pc1/pm40295764-258-8-13?v=Addgene+inc
    Average 93 stars, based on 1 article reviews
    pc1 plasmid backbone - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Appearance and behavior of the HeLa TPI E105D-GF-HR cell line. Upper panel. Representative images of cells expressing mutant TPI-GFP (green) and a HyPerRed ROS biosensor (orange). Nuclei were counterstained with Hoechst 33342 (blue). Images were acquired on an OPERA Phenix Plus using a 63x water immersion objective in the DAPI, GFP, and Cy3 channel. Lower panel. Quantification of cellular response to test agents reveals desirable (elevated GFP in the absence of nuclear shrinkage and elevated ROS; luminespib) and undesirable activity profiles (elevated GFP correlating with nuclear shrinkage and elevated ROS; CID 3724239). Y-axes show percent increases compared with vehicle-treated cells. Data points are the average of at least three independent biological repeats ± SD. Curves were fitted to a four parameter logistic regression. Green, GFP-TPI levels, red, ROS, blue, nucleus size. Images were subjected to identical linear bitmap stretch for visibility.

    Journal: SLAS discovery : advancing life sciences R & D

    Article Title: Discovery and validation of small molecule stabilizers of mutant triose phosphate isomerase (TPI) as potential lead candidates for TPI deficiency

    doi: 10.1016/j.slasd.2025.100278

    Figure Lengend Snippet: Appearance and behavior of the HeLa TPI E105D-GF-HR cell line. Upper panel. Representative images of cells expressing mutant TPI-GFP (green) and a HyPerRed ROS biosensor (orange). Nuclei were counterstained with Hoechst 33342 (blue). Images were acquired on an OPERA Phenix Plus using a 63x water immersion objective in the DAPI, GFP, and Cy3 channel. Lower panel. Quantification of cellular response to test agents reveals desirable (elevated GFP in the absence of nuclear shrinkage and elevated ROS; luminespib) and undesirable activity profiles (elevated GFP correlating with nuclear shrinkage and elevated ROS; CID 3724239). Y-axes show percent increases compared with vehicle-treated cells. Data points are the average of at least three independent biological repeats ± SD. Curves were fitted to a four parameter logistic regression. Green, GFP-TPI levels, red, ROS, blue, nucleus size. Images were subjected to identical linear bitmap stretch for visibility.

    Article Snippet: A construct with the EF1 promoter driving HyperRed protein expression was generated using a HyperRed clone (Addgene # 48,249 [ ], and standard cloning techniques.

    Techniques: Expressing, Mutagenesis, Activity Assay